Molecular Formula | C13H22O4 |
Molar Mass | 242.31138 |
Density | 1.026±0.06 g/cm3(Predicted) |
Boling Point | 377.2±25.0 °C(Predicted) |
Solubility | DMSO : 150 mg/mL (619.04 mM) |
pKa | 3.84±0.11(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
Physical and Chemical Properties | Bioactive 4-Octyl Itaconate is a Itaconate derivative that can be transmitted through cells. Itaconate is an anti-inflammatory metabolite that activates Nrf2 by alkylation of KEAP1. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 4.127 ml | 20.635 ml | 41.269 ml |
5 mM | 0.825 ml | 4.127 ml | 8.254 ml |
10 mM | 0.413 ml | 2.063 ml | 4.127 ml |
5 mM | 0.083 ml | 0.413 ml | 0.825 ml |
Target
Nrf2
In vivo studies
4-Octyl Itaconate (OI) is a cell-permeable itaconate derivative. 4-Octyl Itaconate is protective against lipopolysaccharide-induced lethality in vivo and decreases cytokine production.